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| Brand Name | AXILIEVA 5 mg |
| Composition | Axitinib — 5 mg |
| Manufacture By | Allieva Pharma Private Limited |
| Form | Tablet |
| Packing | Btl (28 Tab) |
| Country Of Origin | India |
| Description | Axilieva 5 mg contains Axitinib, a potent and selective tyrosine kinase inhibitor that acts on VEGFR-1, VEGFR-2, and VEGFR-3. It works by blocking the signals that promote tumor angiogenesis (formation of new blood vessels). By reducing blood supply to the tumor, Axitinib helps: Slow tumor growth Reduce spread Improve progression-free survival It is mainly used when previous cancer treatments have not been effective. |
| Uses | Axilieva (Axitinib) is prescribed for: 1. Advanced Renal Cell Carcinoma (RCC) Used as second-line therapy after failure of earlier treatments such as: Sunitinib Bevacizumab + Interferon Temsirolimus Cytokine therapy 2. First-line therapy Sometimes used in combination with immune checkpoint inhibitors (doctor’s decision). |
| Side Effects | ➢Common Side Effects High blood pressure (hypertension) Diarrhea Fatigue or weakness Loss of appetite Nausea or vomiting Weight loss Hoarseness of voice Hand-foot syndrome Hypothyroidism Joint or muscle pain ➢ Less Common but Serious Blood clots Heart failure Severe bleeding Liver toxicity Gastrointestinal perforation Protein in urine (proteinuria) ➢ Seek immediate help if: Sudden chest pain Severe headache Shortness of breath Heavy bleeding Yellowing of eyes/skin |
| Dosage | Only take as directed by an oncologist. ➢ Standard Adult Dose 5 mg twice daily Approximately 12 hours apart Take with or without food Swallow tablets whole with water ➢ Dose Adjustments Dose may be increased or decreased depending on: Tolerability Blood pressure Liver function Side effects Common adjusted doses: 2 mg, 3 mg, 7 mg, or 10 mg per day. |