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    Fosaprepitant Dimeglumine for Injection 150mg

    Fosaprepitant Dimeglumine for Injection 150mg


    Brand NameAPRELIEVA 150MG
    CompositionFosaaprepitant Dimeglumine for Injection 150mg
    Manufacture ByAllieva Pharma Private Limited
    FormInjection
    PackingVial
    Country Of OriginIndia

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    Description

    Description

    APRELIEVA 150 mg contains Fosaprepitant Dimeglumine, a neurokinin-1 (NK1) receptor antagonist. It is a prodrug of aprepitant and works by blocking substance P in the brain, thereby preventing chemotherapy-induced nausea and vomiting (CINV), especially delayed emesis.

    Uses

    Fosaprepitant is used for prevention of:

    1. Chemotherapy-Induced Nausea and Vomiting (CINV)
        – Associated with highly emetogenic chemotherapy (HEC)
        – Associated with moderately emetogenic chemotherapy (MEC)

    It is used in combination with:

    •  A 5-HT3 receptor antagonist (e.g., ondansetron)

    •  Dexamethasone

    Side Effects

    Common side effects:

    •  Fatigue

    •  Hiccups

    •  Headache

    •  Constipation or diarrhea

    Injection-site reactions:

    •  Pain

    •  Erythema

    •  Phlebitis

    Serious side effects (rare):

    •  Hypersensitivity reactions

    •  Anaphylaxis

    Monitor for infusion-site reactions.

    Dosage

    Standard adult dose:

    •  150 mg IV single dose

    •  Administered 30 minutes before chemotherapy on Day 1

     Replaces 3-day oral aprepitant regimen.

    NOTE: This medicine should be taken only under a doctor’s supervision.

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