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| Brand Name | IBRULIEVA 140MG |
| Composition | Ibrutinib Capsules 140mg |
| Manufacture By | Allieva Pharma Private Limited |
| Form | Capsule |
| Packing | Btl (30 cap) |
| Country Of Origin | India |
| Description | IBRULIEVA contains Ibrutinib, a first-generation Bruton’s Tyrosine Kinase (BTK) inhibitor. It blocks BTK signaling in B-cells, thereby inhibiting the growth and survival of malignant B-lymphocytes. |
| Uses | Ibrutinib is indicated for the treatment of: 1. Chronic Lymphocytic Leukemia (CLL) 2. Small Lymphocytic Lymphoma (SLL) 3. Mantle Cell Lymphoma (MCL) – after at least one prior therapy 4. Waldenström’s Macroglobulinemia 5. Marginal Zone Lymphoma (MZL) – after prior anti-CD20 therapy |
| Side Effects | Common side effects: • Diarrhea • Fatigue • Muscle and joint pain • Nausea • Rash Hematological: • Neutropenia • Thrombocytopenia • Anemia Serious side effects: • Bleeding events • Atrial fibrillation • Severe infections • Hypertension |
| Dosage | Dosage varies by indication: • CLL/SLL/Waldenström’s: 420 mg once daily • MCL/MZL: 560 mg once daily Take capsules once daily at the same time, swallow whole with water.
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