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    Plerixafor Injection 20mg

    Plerixafor Injection 20mg


    Brand NameMOZOLIEVA 20MG
    CompositionPlerixafor Injection 20mg
    Manufacture ByAllieva Pharma Private Limited
    FormInjection
    PackingVial
    Country Of OriginIndia

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    Description

    Description

    MOZOLIEVA 20 mg contains Plerixafor, a hematopoietic stem cell mobilizer. It is a CXCR4 chemokine receptor antagonist that disrupts the interaction between CXCR4 and SDF-1α, causing rapid release of CD34+ stem cells from the bone marrow into peripheral blood for collection.

    Uses

    Plerixafor is used in combination with G-CSF for:

    1. Mobilization of hematopoietic stem cells
       – In patients with Non-Hodgkin’s Lymphoma (NHL)
       – In Multiple Myeloma

    2. Prior to autologous stem cell transplantation

    Side Effects

    Common side effects:

    •  Diarrhea

    •  Nausea

    •  Injection site reactions

    •  Fatigue

    Other side effects:

    •  Dizziness

    •  Headache

    Serious side effects (rare):

    •  Splenic enlargement or rupture

    •  Thrombocytopenia

    Monitor WBC count and spleen size during treatment.

    Dosage

    Dosage is based on body weight.

    Standard dose:

    •  0.24 mg/kg subcutaneous injection

    •  Given approximately 11 hours before apheresis

    •  Used after 4 days of G-CSF

    20 mg vial is suitable for adult dosing.


    NOTE: This medicine should be taken only under a doctor’s supervision.

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