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Product Details

AFALIEVA 40MG Afatinib Tablets IP 40mg by Allieva Pharma Private Limited
AFALIEVA 40MG image 1 AFALIEVA 40MG image 2

AFALIEVA 40MG ( Afatinib Tablets IP 40mg )

AFALIEVA 40MG is an Tablet medication used for treatment purposes. It is manufactured by Allieva Pharma Private Limited.

AFALIEVA 40MG (Afatinib Tablets IP 40mg) – Product Details
Brand Name AFALIEVA 40MG
Composition Afatinib Tablets IP 40mg
Manufacturer Allieva Pharma Private Limited
Dosage Form Tablet
Packaging Btl (28 tab)
Country of Origin India

About Afatinib Tablets IP 40mg

AFALIEVA 40MG (Afatinib Tablets IP 40mg) is a widely used Tablet medicine manufactured by Allieva Pharma Private Limited. It is commonly prescribed for...

Description

AFALIEVA 40 MG (Afatinib Tablets IP 40 mg) is a prescription targeted anticancer medication containing Afatinib 40 mg, a highly effective tyrosine kinase inhibitor (TKI) used in the treatment of specific types of Non-Small Cell Lung Cancer (NSCLC) associated with Epidermal Growth Factor Receptor (EGFR) mutations. Afatinib is designed to target and block abnormal proteins that drive cancer cell growth, multiplication, and spread throughout the body.

Lung cancer is among the most frequently diagnosed cancers worldwide, and advances in molecular diagnostics have made it possible to identify genetic mutations that can be specifically targeted with precision medicines. Patients whose tumors carry EGFR mutations often benefit from targeted therapies such as Afatinib, which are developed to attack cancer cells more selectively than traditional chemotherapy.

AFALIEVA 40 MG works by irreversibly inhibiting members of the ErbB receptor family, including EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4). These receptors are involved in signaling pathways that regulate cell growth and survival. When mutated, they can cause uncontrolled cancer cell proliferation. By blocking these signals, Afatinib helps slow tumor growth, reduce disease progression, and improve clinical outcomes.

Unlike conventional chemotherapy, which affects both healthy and cancerous cells, targeted therapies focus on specific cancer-driving mechanisms. This approach allows for more personalized treatment and has become a cornerstone of modern oncology.

AFALIEVA 40 MG is commonly prescribed for:

  • EGFR Mutation-Positive Non-Small Cell Lung Cancer (NSCLC)
  • Advanced Non-Small Cell Lung Cancer
  • Metastatic Lung Cancer
  • Locally Advanced Lung Cancer
  • Recurrent Lung Cancer
  • Squamous Cell Carcinoma of the Lung (selected cases)
  • Precision Oncology Treatment Programs
  • Long-Term Targeted Cancer Therapy

Before treatment begins, patients generally undergo molecular testing to confirm the presence of EGFR mutations and determine eligibility for Afatinib therapy.

Manufactured under strict pharmaceutical quality standards, AFALIEVA 40 MG is designed to provide consistent quality, safety, and therapeutic effectiveness.

Patients receiving Afatinib treatment usually require regular monitoring through clinical assessments, blood tests, liver function evaluations, and treatment response reviews to ensure optimal outcomes.

Due to its proven efficacy and targeted mechanism of action, AFALIEVA 40 MG is widely recognized as an important treatment option in modern lung cancer management.


Uses

AFALIEVA 40 MG (Afatinib Tablets IP 40 mg) is primarily used in the treatment and management of EGFR mutation-positive lung cancer.

Common Uses of AFALIEVA 40 MG

1. EGFR Mutation-Positive Non-Small Cell Lung Cancer

The medicine is widely prescribed for patients diagnosed with EGFR-positive NSCLC.

2. Advanced Lung Cancer

Afatinib helps manage advanced-stage lung cancer that cannot be effectively treated with surgery alone.

3. Metastatic Lung Cancer

The medicine may be used when cancer has spread beyond the lungs to other parts of the body.

4. Locally Advanced NSCLC

Doctors may prescribe Afatinib for patients with locally advanced disease requiring targeted therapy.

5. Recurrent Lung Cancer

The medicine may help manage lung cancer that returns after previous treatment.

6. Squamous Cell Carcinoma of the Lung

In selected cases, Afatinib may be used as part of treatment strategies for squamous cell lung cancer.

7. Precision Oncology Programs

The medicine supports personalized treatment approaches based on genetic testing results.

8. Long-Term Disease Management

Afatinib helps delay disease progression and maintain treatment response.


How AFALIEVA 40 MG Works

Afatinib belongs to a class of medicines known as Tyrosine Kinase Inhibitors (TKIs).

AFALIEVA works by:

  • Blocking EGFR signaling pathways
  • Inhibiting HER2 and HER4 receptor activity
  • Preventing cancer cell growth and multiplication
  • Reducing tumor progression
  • Limiting cancer cell survival
  • Promoting cancer cell death

This targeted mechanism helps control cancer growth and supports long-term disease management.


Side Effects

Like all medicines, AFALIEVA 40 MG may cause side effects in some patients. The severity and frequency of side effects can vary depending on individual factors and treatment duration.

Common Side Effects

1. Diarrhea

Diarrhea is one of the most commonly reported side effects and may require medical management.

2. Skin Rash

Patients may develop acne-like skin rashes during treatment.

3. Dry Skin

Skin dryness, irritation, and sensitivity may occur.

4. Mouth Sores

Painful ulcers or inflammation inside the mouth may develop.

5. Nail Disorders

Changes around fingernails and toenails may occur.

6. Loss of Appetite

Reduced appetite may affect nutritional intake.

7. Fatigue

Weakness and tiredness are commonly experienced.

8. Nausea

Some patients may experience mild to moderate nausea.

9. Weight Loss

Weight reduction may occur during prolonged treatment.


Serious Side Effects

Seek immediate medical attention if you experience:

  • Severe diarrhea
  • Difficulty breathing
  • Severe skin reactions
  • Eye pain or vision disturbances
  • Severe dehydration
  • Liver-related symptoms
  • Persistent fever
  • Serious allergic reactions
  • Chest pain

Patients should contact their healthcare provider immediately if serious symptoms occur.


Dosage Information

The dosage of AFALIEVA 40 MG (Afatinib Tablets IP 40 mg) should always be determined by a qualified oncologist.

Factors Affecting Dosage

1. Type of Cancer

The prescribed dosage depends on the cancer diagnosis and mutation profile.

2. Treatment Response

Doctors may adjust dosage according to treatment effectiveness and patient tolerance.

3. Side Effect Severity

Dose modifications may be required if significant side effects develop.

4. Organ Function

Liver and kidney health may influence treatment planning.

5. Overall Health Status

Individual patient factors contribute to dosage decisions.


Important Dosage Instructions

  • Take the medicine exactly as prescribed by your doctor.
  • Swallow the tablet whole with water.
  • Take the medicine on an empty stomach if advised by your healthcare provider.
  • Follow all scheduled medical appointments.
  • Do not skip doses without consulting your doctor.
  • Do not discontinue treatment without medical advice.

Precautions Before Using AFALIEVA 40 MG

Before starting treatment, inform your doctor if you have:

  • Liver disease
  • Kidney disease
  • Lung disorders
  • Eye problems
  • Heart disease
  • Active infections
  • Previous reactions to targeted therapies
  • Allergies to Afatinib or related medicines

Patients should also disclose all prescription medicines, supplements, and herbal products they are currently taking to avoid potential drug interactions.

Pregnant or breastfeeding women should only use this medicine if specifically recommended by a healthcare professional.


Storage Instructions

  • Store in a cool and dry place.
  • Protect from moisture and direct sunlight.
  • Keep out of reach of children.
  • Store according to manufacturer recommendations.

Why Choose AFALIEVA 40 MG?

  • Trusted Afatinib formulation
  • Advanced targeted therapy for EGFR-positive lung cancer
  • Supports personalized cancer treatment strategies
  • Manufactured under strict pharmaceutical quality standards
  • Reliable therapeutic performance
  • Suitable for advanced and metastatic NSCLC
  • Helps support long-term disease control
  • Designed for modern precision oncology care

Frequently Asked Questions (FAQs)

What is AFALIEVA 40 MG used for?

It is primarily used for the treatment of EGFR mutation-positive Non-Small Cell Lung Cancer (NSCLC).

What is Afatinib?

Afatinib is a targeted anticancer medicine that blocks EGFR and related receptors involved in cancer cell growth and survival.

Is AFALIEVA 40 MG chemotherapy?

No. It is a targeted therapy that works differently from traditional chemotherapy medicines.

Why is genetic testing necessary before treatment?

Genetic testing helps determine whether the cancer contains EGFR mutations that are likely to respond to Afatinib therapy.

Can AFALIEVA 40 MG cause skin problems?

Yes. Skin rash, dry skin, and nail changes are among the commonly reported side effects.

Is diarrhea common during treatment?

Yes. Diarrhea is one of the most common side effects and should be managed under medical supervision.

Does AFALIEVA 40 MG require regular monitoring?

Yes. Routine blood tests, liver assessments, and clinical evaluations are important throughout treatment.

Should AFALIEVA 40 MG be taken under medical supervision?

Yes. This medicine should only be used under the supervision of qualified healthcare professionals experienced in oncology and targeted cancer treatment.


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