info@allievapharma.com

  • 24/7
    Customer Service
  • ISO 9001
    Certification Company
  • WHO-GMP
    Certified Company

Product Details

TREXLIEVA 500MG Methotrexate Injection 500mg by Allieva Pharma Private Limited
TREXLIEVA 500MG image 1 TREXLIEVA 500MG image 2

TREXLIEVA 500MG ( Methotrexate Injection 500mg )

TREXLIEVA 500MG is an Injection medication used for treatment purposes. It is manufactured by Allieva Pharma Private Limited.

TREXLIEVA 500MG (Methotrexate Injection 500mg) – Product Details
Brand Name TREXLIEVA 500MG
Composition Methotrexate Injection 500mg
Manufacturer Allieva Pharma Private Limited
Dosage Form Injection
Packaging Vial
Country of Origin India

About Methotrexate Injection 500mg

TREXLIEVA 500MG (Methotrexate Injection 500mg) is a widely used Injection medicine manufactured by Allieva Pharma Private Limited. It is commonly prescribed for...

Description

TREXLIEVA 500 MG (Methotrexate Injection 500 mg) is a prescription medicine containing Methotrexate 500 mg, a widely used antimetabolite and antifolate agent utilized in the treatment of various cancers, autoimmune disorders, and certain severe inflammatory conditions. In oncology, Methotrexate plays a critical role in controlling the growth and spread of rapidly dividing cancer cells by interfering with DNA synthesis and cellular replication.

Methotrexate has been an important component of cancer treatment protocols for several decades and is used in hospitals and specialized oncology centers worldwide. It is commonly prescribed for cancers such as Acute Lymphoblastic Leukemia (ALL), Non-Hodgkin Lymphoma, Osteosarcoma, Breast Cancer, Head and Neck Cancer, and certain other malignancies. The medicine may also be used in selected non-cancer conditions under strict medical supervision.

Cancer cells multiply rapidly and require folic acid to produce DNA and grow. TREXLIEVA 500 MG works by blocking the enzyme Dihydrofolate Reductase (DHFR), which is essential for folic acid metabolism. By disrupting this process, Methotrexate prevents cancer cells from producing the DNA necessary for growth and division, ultimately leading to cell death.

TREXLIEVA 500 MG is commonly used for:

  • Acute Lymphoblastic Leukemia (ALL)
  • Non-Hodgkin Lymphoma
  • Osteosarcoma
  • Breast Cancer
  • Head and Neck Cancer
  • Gestational Trophoblastic Neoplasia
  • Central Nervous System Prophylaxis in Leukemia
  • Combination Chemotherapy Programs
  • Advanced Oncology Treatment Protocols

The medicine may be administered alone or in combination with other anticancer medicines depending on the type of cancer, disease stage, and treatment goals. High-dose Methotrexate therapy is often followed by specialized supportive care measures, including leucovorin rescue, to help reduce toxicity.

Manufactured under strict pharmaceutical quality standards, TREXLIEVA 500 MG is designed to provide consistent therapeutic performance, safety, and reliability. The injection should only be administered by qualified healthcare professionals experienced in oncology and chemotherapy treatment.

Patients receiving Methotrexate therapy typically require regular monitoring through blood tests, liver function assessments, kidney function evaluations, and routine clinical examinations to ensure safe and effective treatment.

Due to its proven efficacy and broad therapeutic applications, TREXLIEVA 500 MG remains an essential medicine in modern oncology and specialized medical care.


Uses

TREXLIEVA 500 MG (Methotrexate Injection 500 mg) is primarily used for the treatment of various cancers and specific medical conditions requiring antimetabolite therapy.

Common Uses of TREXLIEVA 500 MG

1. Acute Lymphoblastic Leukemia (ALL)

The medicine is widely used in leukemia treatment protocols to help control abnormal white blood cell growth.

2. Non-Hodgkin Lymphoma

Methotrexate may be prescribed as part of comprehensive lymphoma treatment plans.

3. Osteosarcoma

The medicine plays an important role in certain treatment protocols for bone cancer.

4. Breast Cancer

TREXLIEVA may be included in selected chemotherapy regimens for breast cancer management.

5. Head and Neck Cancer

Doctors may prescribe Methotrexate to help control tumor growth in specific cancers of the head and neck region.

6. Gestational Trophoblastic Neoplasia

The medicine is used in the treatment of trophoblastic tumors and related conditions.

7. Combination Chemotherapy Programs

Methotrexate is frequently administered alongside other anticancer medicines to improve treatment outcomes.

8. Advanced Oncology Care

The medicine supports comprehensive cancer treatment strategies across multiple malignancies.


How TREXLIEVA 500 MG Works

Methotrexate belongs to a class of medicines known as Antimetabolites and Antifolate Agents.

TREXLIEVA works by:

  • Blocking Dihydrofolate Reductase (DHFR)
  • Inhibiting folic acid metabolism
  • Preventing DNA synthesis
  • Slowing cancer cell growth
  • Interfering with cell division
  • Promoting cancer cell death

This mechanism helps control disease progression and improve cancer treatment outcomes.


Side Effects

Like all chemotherapy medicines, TREXLIEVA 500 MG may cause side effects in some patients. Side effects vary depending on dosage, treatment duration, and individual patient factors.

Common Side Effects

1. Nausea

Patients may experience mild to moderate nausea during treatment.

2. Vomiting

Episodes of vomiting may occur following administration.

3. Fatigue

Weakness and tiredness are commonly reported.

4. Loss of Appetite

Reduced appetite may affect nutritional intake.

5. Mouth Sores

Oral ulcers and mouth irritation may develop during therapy.

6. Diarrhea

Digestive disturbances and loose stools may occur.

7. Hair Thinning

Temporary hair loss or thinning may develop in some patients.

8. Skin Sensitivity

Some individuals may experience skin-related reactions.

9. Low Blood Cell Counts

Methotrexate may reduce:

  • White blood cells
  • Red blood cells
  • Platelets

This may increase the risk of infections, anemia, and bleeding complications.


Serious Side Effects

Seek immediate medical attention if you experience:

  • Severe infection symptoms
  • High fever
  • Difficulty breathing
  • Severe allergic reactions
  • Persistent vomiting
  • Severe mouth ulcers
  • Liver-related symptoms
  • Kidney-related complications
  • Unusual bleeding or bruising

Patients should immediately contact their healthcare provider if serious symptoms occur.


Dosage Information

The dosage of TREXLIEVA 500 MG (Methotrexate Injection 500 mg) should always be determined by a qualified oncologist or healthcare professional.

Factors Affecting Dosage

1. Type of Disease

Different cancers and medical conditions require different treatment schedules.

2. Body Surface Area (BSA)

Dosage is commonly calculated according to body size.

3. Kidney Function

Kidney health significantly influences Methotrexate dosing.

4. Liver Function

Patients with liver impairment may require special monitoring and dosage adjustments.

5. Treatment Response

Doctors may modify therapy based on effectiveness and side effect management.


Important Dosage Instructions

  • The injection should only be administered by trained healthcare professionals.
  • Follow all prescribed treatment schedules carefully.
  • Attend regular blood tests and monitoring appointments.
  • Maintain adequate hydration as advised by your healthcare provider.
  • Inform your doctor about any unusual symptoms during therapy.
  • Do not alter treatment schedules without medical supervision.

Precautions Before Using TREXLIEVA 500 MG

Before receiving treatment, patients should inform their doctor if they have:

  • Liver disease
  • Kidney disease
  • Blood disorders
  • Active infections
  • Lung disease
  • Previous chemotherapy-related complications
  • Allergies to Methotrexate or related medicines

Patients should also disclose all prescription medicines, supplements, and herbal products they are currently taking to avoid potential drug interactions.

Pregnant women should not receive Methotrexate unless specifically recommended by a healthcare professional, as the medicine may cause serious harm to an unborn baby.

Breastfeeding should generally be avoided during treatment unless advised otherwise by a healthcare provider.


Storage Instructions

  • Store according to manufacturer recommendations.
  • Protect from direct sunlight and excessive heat.
  • Keep out of reach of children.
  • Follow hospital and pharmacy storage guidelines.

Why Choose TREXLIEVA 500 MG?

  • Trusted Methotrexate formulation
  • Effective treatment option for multiple cancers
  • Supports established chemotherapy protocols
  • Manufactured under strict pharmaceutical quality standards
  • Reliable therapeutic performance
  • Suitable for advanced oncology care
  • Helps support comprehensive cancer treatment programs

Frequently Asked Questions (FAQs)

What is TREXLIEVA 500 MG used for?

It is used for the treatment of various cancers including leukemia, lymphoma, osteosarcoma, breast cancer, and certain trophoblastic tumors.

What is Methotrexate?

Methotrexate is an antimetabolite and antifolate medicine that interferes with DNA synthesis and cancer cell growth.

Is TREXLIEVA 500 MG a chemotherapy medicine?

Yes, it is a widely used chemotherapy medicine utilized in several oncology treatment protocols.

Can TREXLIEVA 500 MG be used with other anticancer medicines?

Yes, it is frequently included in combination chemotherapy regimens.

Does TREXLIEVA affect blood cell counts?

Yes, the medicine may lower white blood cells, red blood cells, and platelets, requiring regular monitoring.

Why is kidney monitoring important during treatment?

Methotrexate is primarily eliminated through the kidneys, making kidney function monitoring essential for patient safety.

Is regular monitoring necessary during treatment?

Yes, doctors typically recommend blood tests, liver function assessments, kidney evaluations, and routine medical examinations throughout therapy.

Should TREXLIEVA 500 MG be administered under medical supervision?

Yes, this medicine should only be administered by qualified healthcare professionals experienced in oncology, chemotherapy, and specialized cancer treatment.


24/7 Clients Support

Best Price

Quality Assurance